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What is Pluryal?
Pluryal is a cutting-edge injectable skin treatment that contains polynucleotides (PN)—active ingredients extracted from salmon DNA—to help stimulate the skin’s natural self-regeneration. Unlike hyaluronic acid fillers, which primarily add volume, Pluryal works at the cellular level to promote the production of collagen and elastin. It helps restore firmness and elasticity lost through aging or damage, leading to smoother, more refined skin with less visible pores and improved texture.
Treatment Features
What makes it different from other injectable treatments?
Pluryal is a treatment specialized in “repair”—it activates the skin’s foundational cells to support recovery and regeneration.
High tissue-repair ability (the power of polynucleotides)
The key ingredient, PN, strongly supports the repair of damaged skin tissue. By helping reduce inflammation and promoting new blood vessel formation, it regenerates the skin from within into a healthier state.
Natural-looking results without affecting facial expressions
Because it stimulates regeneration from deep within the skin, it is ideal for tightening the appearance of pores and improving uneven texture from acne scars. This approach works from the skin’s foundation—beyond what surface-level skincare can reach.
Effective even for delicate areas (around the eyes and neck)
It delivers strong results in areas that are thin and sensitive, such as under-eye dark circles and fine lines, as well as horizontal neck lines—areas that have traditionally been difficult to treat.
Fewer side effects and high safety
Because it uses ingredients with high biocompatibility, the risk of allergic reactions is very low, allowing you to undergo the treatment with peace of mind.
Prevents skin irritation with anti-inflammatory and antioxidant effects
By strengthening the skin’s barrier function, it helps improve redness and supports building resilient skin that can better withstand external irritants.
Yoshiko Kuno